Dr. Deepak Aiwale

migraine treatment when painkillers don’t work

When standard migraine treatment with common painkillers fails, the result can be disabling. Many experience only temporary relief or find their medications stop working entirely, leaving them to suffer unaware that advanced neurological options exist. This is where a personalized migraine treatment plan, guided by an experienced neurologist, becomes crucial. By identifying the root causes of your pain, such an approach can significantly reduce both the frequency and severity of attacks.

Understanding Why Painkillers Stop Working

For many migraine sufferers, over the counter painkillers such as paracetamol, aspirin, or ibuprofen only provide short term relief. In some cases, they don’t work at all. Here are some reasons:

Medication Overuse Headache (MOH)

Using painkillers too frequently can cause rebound headaches, making migraines worse instead of better. This complicates Migraine Treatment, as the brain becomes more sensitive to pain.

Not all severe headaches are migraines. Sometimes sinus headaches, tension headaches, or cluster headaches are misdiagnosed, leading to the wrong treatment.

Migraines often evolve from episodic (less frequent) to chronic (15+ headache days per month), requiring stronger preventive therapies.

Triggers like stress, hormonal changes, sleep issues, dehydration, and diet can make painkillers ineffective if not addressed.

Next Level Migraine Treatment Options When Painkillers Fail

Prescription Medications Designed Specifically for Migraines

Triptans

Used for moderate to severe migraines. They reduce inflammation in blood vessels and work faster than OTC medicines.

These block the CGRP pathway, which plays a key role in migraine pain. They are ideal for people who cannot take triptans.

Very effective for acute migraine attacks without causing rebound headaches.

Preventive Migraine Therapy

If you experience more than four migraine attacks per month, preventive medicines may help.

Common preventive options include:

  • Anticonvulsants
  • Beta-blockers
  • Antidepressants
  • CGRP monoclonal antibodies (a breakthrough in Migraine Treatment)

These work by calming the brain’s pain pathways.

 

Botox Injections for Chronic Migraine

Botox is FDA-approved for chronic migraine and is used widely by neurologists.
It works by relaxing muscles and blocking nerve signals responsible for pain.

Why Botox Works Well:

  • Reduces headache frequency

  • Minimal side effects

Especially useful when medications fail

Nerve Blocks

A quick, clinic based procedure where local anaesthesia is injected around certain nerves in the head or neck.

Benefits:

  • Instant relief for many patients
  • Reduces migraine frequency

Useful for patients who cannot take medications

Neuromodulation Devices

These are external devices that use magnetic or electrical pulses to calm brain activity.

Options Include:

  • Transcranial magnetic stimulation (TMS)

  • Vagus nerve stimulation

  • External trigeminal nerve stimulation

These represent the future of drug-free Migraine Treatment.

Lifestyle & Trigger Management

A neurologist focuses not just on medicine but also on long-term control.

Important steps:

  • Sleep regulation

  • Stress reduction

  • Hydration

  • Avoiding processed foods

  • Managing screen time

These changes significantly reduce migraine frequency.

FAQs About Migraine Treatment

When should I see a neurologist for migraine?

If painkillers no longer work, or you experience frequent headaches, vomiting, visual disturbances, or headaches lasting more than 72 hours, visit a neurologist immediately.

Migraines cannot be fully cured, but with proper Migraine Treatment, they can be controlled so effectively that you experience fewer and less severe attacks.

Yes. Botox for migraine is FDA-approved and considered very safe when administered by a trained specialist like Dr Deepak Aiwale.

CGRP-blocking medications, gepants, ditans, Botox, nerve blocks, and neuromodulation devices are among the most advanced modern treatments.

Absolutely. Sleep, hydration, stress management, and diet play a major role in preventing migraines.

Conclusion

If you are tired of repeated headaches or painkillers no longer work, it’s time to seek a specialist.
Dr Deepak Aiwale, an experienced neurologist, provides advanced and personalised migraine treatments that target the root cause of your headache.

Contact Details

Dr Deepak Aiwale-Best Neurologist in Thane

Solaris Hospital, Ghodbunder Road, Service Road, Next to A.P. Shah Technology Institute, Kasarvadavali, Thane West, Thane, Maharashtra 400615

For Appointment

Timings

Open: 07:00 AM - 11:30 PM

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